Hypoxic pulmonary vasoconstriction requires connexin 40–mediated endothelial signal conduction

Hypoxic pulmonary vasoconstriction (HPV) is a physiological mechanism by which pulmonary arteries constrict in hypoxic lung areas in order to redirect blood flow to areas with greater oxygen supply. Both oxygen sensing and the contractile response are thought to be intrinsic to pulmonary arterial sm...

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Auteurs principaux: Wang, Liming, Yin, Jun, Nickles, Hannah T., Ranke, Hannes, Tabuchi, Arata, Hoffmann, Julia, Tabeling, Christoph, Barbosa-Sicard, Eduardo, Chanson, Marc, Kwak, Brenda R., Shin, Hee-Sup, Wu, Songwei, Isakson, Brant E., Witzenrath, Martin, de Wit, Cor, Fleming, Ingrid, Kuppe, Hermann, Kuebler, Wolfgang M.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484430/
https://ncbi.nlm.nih.gov/pubmed/23093775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59176
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