HOTAIR IS A NEGATIVE PROGNOSTIC FACTOR AND EXHIBITS PRO-ONCOGENIC ACTIVITY IN PANCREATIC CANCER

HOTAIR is a long intervening non-coding RNA (lincRNA) that associates with the Polycomb Repressive Complex 2 (PRC2) and overexpression is correlated with poor survival for breast, colon and liver cancer patients. In this study, we show that HOTAIR expression is increased in pancreatic tumors compare...

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Detalhes bibliográficos
Main Authors: Kim, Kyounghyun, Jutooru, Indira, Chadalapaka, Gayathri, Johnson, Greg, Frank, James, Burghardt, Robert, Kim, Sangbae, Safe, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484248/
https://ncbi.nlm.nih.gov/pubmed/22614017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.193
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