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Docosahexaenoic Acid Signaling Modulates Cell Survival in Experimental Ischemic Stroke Penumbra and Initiates Long-Term Repair in Young and Aged Rats

BACKGROUND: Docosahexaenoic acid, a major omega-3 essential fatty acid family member, improves behavioral deficit and reduces infarct volume and edema after experimental focal cerebral ischemia. We hypothesize that DHA elicits neuroprotection by inducing AKT/p70S6K phosphorylation, which in turn lea...

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Hlavní autoři: Eady, Tiffany N., Belayev, Ludmila, Khoutorova, Larissa, Atkins, Kristal D., Zhang, Changde, Bazan, Nicolas G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484151/
https://ncbi.nlm.nih.gov/pubmed/23118851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046151
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