Docosahexaenoic Acid Signaling Modulates Cell Survival in Experimental Ischemic Stroke Penumbra and Initiates Long-Term Repair in Young and Aged Rats

BACKGROUND: Docosahexaenoic acid, a major omega-3 essential fatty acid family member, improves behavioral deficit and reduces infarct volume and edema after experimental focal cerebral ischemia. We hypothesize that DHA elicits neuroprotection by inducing AKT/p70S6K phosphorylation, which in turn lea...

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Bibliografiske detaljer
Main Authors: Eady, Tiffany N., Belayev, Ludmila, Khoutorova, Larissa, Atkins, Kristal D., Zhang, Changde, Bazan, Nicolas G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484151/
https://ncbi.nlm.nih.gov/pubmed/23118851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046151
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