Hepatitis B viral core protein disrupts human host gene expression by binding to promoter regions

BACKGROUND: The core protein (HBc) of hepatitis B virus (HBV) has been implicated in the malignant transformation of chronically-infected hepatocytes and displays pleiotropic functions, including RNA- and DNA-binding activities. However, the mechanism by which HBc interacts with the human genome to...

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Detalhes bibliográficos
Main Authors: Guo, Yanhai, Kang, Wei, Lei, Xiaoying, Li, Yongnian, Xiang, An, Liu, Yonglan, Zhao, Jinrong, Zhang, Ju, Yan, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484065/
https://ncbi.nlm.nih.gov/pubmed/23088787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-563
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