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Mechanisms of Xenogeneic Baboon Platelet Aggregation and Phagocytosis by Porcine Liver Sinusoidal Endothelial Cells

BACKGROUND: Baboons receiving xenogeneic livers from wild type and transgenic pigs survive less than 10 days. One of the major issues is the early development of profound thrombocytopenia that results in fatal hemorrhage. Histological examination of xenotransplanted livers has shown baboon platelet...

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Detalhes bibliográficos
Main Authors: Peng, Qiang, Yeh, Heidi, Wei, Lingling, Enjyoj, Keiichi, Machaidze, Zurab, Csizmad, Eva, Schuetz, Christian, Lee, Kang Mi, Deng, Shaoping, Robson, Simon C., Markmann, James, Buhler, Leo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484054/
https://ncbi.nlm.nih.gov/pubmed/23118867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047273
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