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Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes.

Treatment of rats with phenobarbital leads to a substantial increase in levels of translatable liver cytochrome P-450 mRNA. This mRNA is primarily associated with ribosomes bound to endoplasmic reticulum membranes which in an in vitro system synthesized approximately 10 times more cytochrome P-450 t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bar-Nun, S, Kreibich, G, Adesnik, M, Alterman, L, Negishi, M, Sabatini, D D
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348404/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6767247/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.2.965
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