Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes.

Treatment of rats with phenobarbital leads to a substantial increase in levels of translatable liver cytochrome P-450 mRNA. This mRNA is primarily associated with ribosomes bound to endoplasmic reticulum membranes which in an in vitro system synthesized approximately 10 times more cytochrome P-450 t...

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Bibliographic Details
Main Authors: Bar-Nun, S, Kreibich, G, Adesnik, M, Alterman, L, Negishi, M, Sabatini, D D
Format: Artigo
Language:Inglês
Published: 1980
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC348404/
https://ncbi.nlm.nih.gov/pubmed/6767247
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