Ileal Inflammation May Trigger the Development of GP2-Specific Pancreatic Autoantibodies in Patients with Crohn's Disease

Why zymogen glycoprotein 2 (GP2), the Crohn's disease (CD)-specific pancreatic autoantigen, is the major target of humoral autoimmunity in inflammatory bowel diseases (IBD) is uknown. Recent evidence demonstrates that GP2 is also present on the apical surface of microfold (M) intestinal cells....

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Hlavní autoři: Pavlidis, Polychronis, Romanidou, Ourania, Roggenbuck, Dirk, Mytilinaiou, Maria G., Al-Sulttan, Faris, Liaskos, Christos, Smyk, Daniel S., Koutsoumpas, Andreas L., Rigopoulou, Eirini I., Conrad, Karsten, Forbes, Alastair, Bogdanos, Dimitrios P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2012
Témata:
Clinical Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483735/
https://ncbi.nlm.nih.gov/pubmed/23118780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/640835
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