Ileal Inflammation May Trigger the Development of GP2-Specific Pancreatic Autoantibodies in Patients with Crohn's Disease

Why zymogen glycoprotein 2 (GP2), the Crohn's disease (CD)-specific pancreatic autoantigen, is the major target of humoral autoimmunity in inflammatory bowel diseases (IBD) is uknown. Recent evidence demonstrates that GP2 is also present on the apical surface of microfold (M) intestinal cells....

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Detalhes bibliográficos
Main Authors: Pavlidis, Polychronis, Romanidou, Ourania, Roggenbuck, Dirk, Mytilinaiou, Maria G., Al-Sulttan, Faris, Liaskos, Christos, Smyk, Daniel S., Koutsoumpas, Andreas L., Rigopoulou, Eirini I., Conrad, Karsten, Forbes, Alastair, Bogdanos, Dimitrios P.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483735/
https://ncbi.nlm.nih.gov/pubmed/23118780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/640835
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