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Long-timescale dynamics and regulation of Sec-facilitated protein translocation
We present a coarse-grained modeling approach that spans the nanosecond- to minute-timescale dynamics of co-translational protein translocation. The method enables direct simulation of both integral membrane protein topogenesis and transmembrane domain (TM) stop-transfer efficiency. Simulations reve...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483636/ https://ncbi.nlm.nih.gov/pubmed/23084746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.08.039 |
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