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A genetically encoded metabolite sensor for malonyl-CoA
Malonyl-CoA is the rate determining metabolite for long chain de novo fatty acid synthesis and allosterically inhibits the rate-setting step in long chain fatty acid β-oxidation. We have developed a cell-based genetically encoded biosensor based on the malonyl-CoA responsive Bacillus subtilis transc...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483566/ https://ncbi.nlm.nih.gov/pubmed/23102226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.08.018 |
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