Covalent labeling of protein components of the sodium channel with a photoactivable derivative of scorpion toxin.
Azidonitrobenzoyl mono[125I]iodo scorpion toxin can be covalently attached to its receptor site in electrically excitable neuroblastoma cells or synaptosomes by photolysis. A polypeptide of Mr approximately 250,000 is specifically labeled in neuroblastoma cells. Labeling is blocked by unlabeled scor...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1980
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348330/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6928649/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.1.639 |
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