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Covalent labeling of protein components of the sodium channel with a photoactivable derivative of scorpion toxin.

Azidonitrobenzoyl mono[125I]iodo scorpion toxin can be covalently attached to its receptor site in electrically excitable neuroblastoma cells or synaptosomes by photolysis. A polypeptide of Mr approximately 250,000 is specifically labeled in neuroblastoma cells. Labeling is blocked by unlabeled scor...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Beneski, D A, Catterall, W A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348330/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6928649/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.1.639
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