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Adaptive evolution of Toll-like receptor 5 in domesticated mammals

BACKGROUND: Previous studies have proposed that mammalian toll like receptors (TLRs) have evolved under diversifying selection due to their role in pathogen detection. To determine if this is the case, we examined the extent of adaptive evolution in the TLR5 gene in both individual species and defin...

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Bibliografiske detaljer
Main Authors: Smith, Sarah A, Jann, Oliver C, Haig, David, Russell, George C, Werling, Dirk, Glass, Elizabeth J, Emes, Richard D
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483281/
https://ncbi.nlm.nih.gov/pubmed/22827462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-12-122
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