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Molecular evolution of bovine Toll-like receptor 2 suggests substitutions of functional relevance

BACKGROUND: There is accumulating evidence that polymorphism in Toll-like receptor (TLR) genes might be associated with disease resistance or susceptibility traits in livestock. Polymorphic sites affecting TLR function should exhibit signatures of positive selection, identified as a high ratio of no...

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Autori principali: Jann, Oliver C, Werling, Dirk, Chang, Jung-Su, Haig, David, Glass, Elizabeth J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588590/
https://ncbi.nlm.nih.gov/pubmed/18937834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-288
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