Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice

BACKGROUND: Alzheimer’s disease (AD) is the most prevalent form of age-related dementia, and its effect on society increases exponentially as the population ages. Accumulating evidence suggests that neuroinflammation, mediated by the brain’s innate immune system, contributes to AD neuropathology and...

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Main Authors: Krstic, Dimitrije, Madhusudan, Amrita, Doehner, Jana, Vogel, Prisca, Notter, Tina, Imhof, Claudine, Manalastas, Abigail, Hilfiker, Martina, Pfister, Sandra, Schwerdel, Cornelia, Riether, Carsten, Meyer, Urs, Knuesel, Irene
格式: Artigo
語言:Inglês
出版: BioMed Central 2012
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483167/
https://ncbi.nlm.nih.gov/pubmed/22747753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-151
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