SH2D2A Modulates T Cell Mediated Protection to a B Cell Derived Tumor in Transgenic Mice

BACKGROUND: T cell specific adapter protein (TSAd), encoded by the SH2D2A gene, modulates signaling downstream of the T cell receptor (TCR). Young, unchallenged SH2D2A-deficient C57BL/6 mice exhibit a relatively normal immune phenotype. To address whether SH2D2A regulates physiologic immune response...

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Autors principals: Berge, Tone, Grønningsæter, Ingrid Helene Bø, Lorvik, Kristina Berg, Abrahamsen, Greger, Granum, Stine, Sundvold-Gjerstad, Vibeke, Corthay, Alexandre, Bogen, Bjarne, Spurkland, Anne
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483153/
https://ncbi.nlm.nih.gov/pubmed/23144743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048239
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