Structure function analysis of SH2D2A isoforms expressed in T cells reveals a crucial role for the proline rich region encoded by SH2D2A exon 7

BACKGROUND: The activation induced T cell specific adapter protein (TSAd), encoded by SH2D2A, interacts with and modulates Lck activity. Several transcript variants of TSAd mRNA exist, but their biological significance remains unknown. Here we examined expression of SH2D2A transcripts in activated C...

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Main Authors: Granum, Stine, Sundvold-Gjerstad, Vibeke, Dai, Ke-Zheng, Kolltveit, Kristin Melkevik, Hildebrand, Kjersti, Huitfeldt, Henrik S, Lea, Tor, Spurkland, Anne
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2006
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1553471/
https://ncbi.nlm.nih.gov/pubmed/16839418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-7-15
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