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The Synthesis and Antimicrobial Activity of Heterocyclic Derivatives of Totarol

[Image: see text] The synthesis and antimicrobial activity of heterocyclic analogues of the diterpenoid totarol are described. An advanced synthetic intermediate with a ketone on the A-ring is used to attach fused heterocycles, and a carbon-to-nitrogen atom replacement is made on the B-ring by de no...

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Bibliografiske detaljer
Main Authors: Kim, Michelle B., O'Brien, Terrence E., Moore, Jared T., Anderson, David E., Foss, Marie H., Weibel, Douglas B., Ames, James B., Shaw, Jared T.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2012
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483140/
https://ncbi.nlm.nih.gov/pubmed/23119123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml3001775
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