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Membrane Voltage Fluctuations Reduce Spike Frequency Adaptation and Preserve Output Gain in CA1 Pyramidal Neurons in a High-Conductance State

Modulating the gain of the input–output function of neurons is critical for processing of stimuli and network dynamics. Previous gain control mechanisms have suggested that voltage fluctuations play a key role in determining neuronal gain in vivo. Here we show that, under increased membrane conducta...

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Detalhes bibliográficos
Main Authors: Fernandez, Fernando R., Broicher, Tilman, Truong, Alan, White, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483084/
https://ncbi.nlm.nih.gov/pubmed/21389243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5076-10.2011
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