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Endogenous Androgen Deficiency Enhances Diet-Induced Hypercholesterolemia and Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice

BACKGROUND: Despite numerous clinical and animal studies, the role of sex steroid hormones on lipoprotein metabolism and atherosclerosis remain controversial. OBJECTIVE: We sought to determine the effects of endogenous estrogen and testosterone on lipoprotein levels and atherosclerosis using mice fe...

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Bibliografiske detaljer
Main Authors: Hatch, Nicholas W., Srodulski, Sarah J., Chan, Huei-Wei, Zhang, Xuan, Tannock, Lisa R., King, Victoria L.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483072/
https://ncbi.nlm.nih.gov/pubmed/22981166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.genm.2012.08.003
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