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Adipocyte-derived soluble factor(s) inhibits early stages of B lymphopoiesis
B lymphopoiesis declines with age, and in rabbit this occurs by 8 weeks of age. We found that colony-forming units fibroblasts (CFU-F) in the bone marrow (BM) decrease 10-fold by a few weeks of age, and that the CFU-Fs preferentially differentiate into adipocytes instead of osteoblasts. BM becomes f...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483032/ https://ncbi.nlm.nih.gov/pubmed/23002443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201176 |
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