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Inhibition of B-lymphopoiesis by Adipocytes and IL-1-producing MDSCs()
B-lymphopoiesis declines with age, and this decline not only correlates with increased adipose tissue in the bone marrow (BM), but also adipocyte-derived factors are known to inhibit B-lymphopoiesis. Using co-cultures of mouse BM cells with OP9 stromal cells, we found that adipocyte-conditioned medi...
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| Publicado no: | J Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4561202/ https://ncbi.nlm.nih.gov/pubmed/26268654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500957 |
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