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Non-randomized mtDNA damage after ionizing radiation via charge transport

Although it is well known that there are mutation hot spots in mtDNA, whether there are damage hot spots remain elusive. In this study, the regional DNA damage of mitochondrial genome after ionizing radiation was determined by real-time quantitative PCR. The mtDNA damage level was found to be dose-d...

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Detalhes bibliográficos
Main Authors: Zhou, Xin, Liu, Xinguo, Zhang, Xin, Zhou, Rong, He, Yang, Li, Qiang, Wang, Zhenhua, Zhang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483021/
https://ncbi.nlm.nih.gov/pubmed/23110249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00780
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