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Syndecan-2 can promote clearance of T-cell receptor/CD3 from the cell surface

T cells express the heparan sulphate proteoglycans syndecan-2 and syndecan-4. Syndecan-4 plays a T-cell inhibitory role; however, the function of syndecan-2 is unknown. In an attempt to examine this function, syndecan-2 was expressed constitutively in Jurkat T cells. Interestingly, the expression of...

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Autori principali: Rovira-Clavé, Xavier, Angulo-Ibáñez, Maria, Noguer, Oriol, Espel, Enric, Reina, Manuel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482679/
https://ncbi.nlm.nih.gov/pubmed/22881146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03626.x
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