Integrative Metabolome and Transcriptome Profiling Reveals Discordant Energetic Stress between Mouse Strains with Differential Sensitivity to Acrolein-Induced Acute Lung Injury

A respiratory irritant, acrolein is generated by overheating cooking oils or by domestic cooking using biomass fuels, and is in tobacco smoke, an occupational health hazard in the restaurant workplace. To better understand the metabolic role of the lung and to generate insights into the pathogenesis...

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Hauptverfasser: Fabisiak, James P., Medvedovic, Mario, Alexander, Danny C., McDunn, Jonathan E., Concel, Vincent J., Bein, Kiflai, Jang, An Soo, Brendt, Annerose, Vuga, Louis J., Brant, Kelly A., Pope-Varsalona, Hannah, Dopico, Richard A., Ganguly, Koustav, Upadhyay, Swapna, Li, Qian, Hu, Zhen, Kaminski, Naftali, Leikauf, George D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482455/
https://ncbi.nlm.nih.gov/pubmed/21823223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201100291
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