Endothelial Dysfunction and Claudin 5 Regulation during Acrolein-Induced Lung Injury

An integral membrane protein, Claudin 5 (CLDN5), is a critical component of endothelial tight junctions that control pericellular permeability. Breaching of endothelial barriers is a key event in the development of pulmonary edema during acute lung injury (ALI). A major irritant in smoke, acrolein c...

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Main Authors: Jang, An Soo, Concel, Vincent J., Bein, Kiflai, Brant, Kelly A., Liu, Shannen, Pope-Varsalona, Hannah, Dopico, Richard A., Di, Y. P. Peter, Knoell, Daren L., Barchowsky, Aaron, Leikauf, George D.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2011
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095921/
https://ncbi.nlm.nih.gov/pubmed/20525806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0391OC
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