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The expression of Delta ligands in the sponge Amphimedon queenslandica suggests an ancient role for Notch signaling in metazoan development

BACKGROUND: Intercellular signaling via the Notch pathway regulates cell fate, patterning, differentiation and proliferation, and is essential for the proper development of bilaterians and cnidarians. To investigate the origins of the Notch pathway, we are studying its deployment in a representative...

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Autors principals: Richards, Gemma S, Degnan, Bernard M
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482393/
https://ncbi.nlm.nih.gov/pubmed/22824137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9139-3-15
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