The expression of Delta ligands in the sponge Amphimedon queenslandica suggests an ancient role for Notch signaling in metazoan development

BACKGROUND: Intercellular signaling via the Notch pathway regulates cell fate, patterning, differentiation and proliferation, and is essential for the proper development of bilaterians and cnidarians. To investigate the origins of the Notch pathway, we are studying its deployment in a representative...

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Bibliographic Details
Main Authors: Richards, Gemma S, Degnan, Bernard M
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482393/
https://ncbi.nlm.nih.gov/pubmed/22824137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9139-3-15
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