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Dysregulation of kappa-opioid receptor systems by chronic nicotine modulate the nicotine withdrawal syndrome in an age-dependent manner
RATIONALE: The mechanisms that mediate age differences during nicotine withdrawal are unclear. OBJECTIVE: This study compared kappa opioid receptor (KOR) activation in naïve and nicotine-treated adolescent and adult rats using behavioral and neurochemical approaches to study withdrawal. METHODS: The...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3482308/ https://ncbi.nlm.nih.gov/pubmed/22659976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-012-2752-7 |
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