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Structure-based prediction of protein-protein interactions on a genome-wide scale

The genome-wide identification of pairs of interacting proteins is an important step in the elucidation of cell regulatory mechanisms(1,2). Much of our current knowledge derives from high-throughput techniques such as yeast two hybrid and affinity purification(3), as well as from manual curation of...

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Autors principals: Zhang, Qiangfeng Cliff, Petrey, Donald, Deng, Lei, Qiang, Li, Shi, Yu, Thu, Chan Aye, Bisikirska, Brygida, Lefebvre, Celine, Accili, Domenico, Hunter, Tony, Maniatis, Tom, Califano, Andrea, Honig, Barry
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482288/
https://ncbi.nlm.nih.gov/pubmed/23023127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11503
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