Effect of cleaving interchain disulfide bridges on the radius of gyration and maximum length of anti-poly(D-alanyl) antibodies before and after reaction with tetraalanine hapten.
The small-angle x-ray scattering of solutions of rabbits IgG antibodies and their derivatives has been investigated. The reduction and alkylation of the native antibody cause a small increase of the molecular parameters, indicating a limited expansion of the molecule. Binding of native antipoly(D-al...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1980
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348219/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6767235/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.1.117 |
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