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THE ROLE OF INNATE IMMUNITY IN THE PATHOGENESIS OF PRENEOPLASIA IN DRUG-INDUCED CHRONIC HEPATITIS BASED ON A MOUSE MODEL

Innate immunity factors such as conversion of the 26S proteasome to form the immunoproteasome and the Toll-like receptor signaling pathways are activated in chronic hepatitis induced by the carcinogenic drug DDC. Over time, preneoplastic hepatocyte phenotypes appear in the liver parenchyma. These ch...

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Main Authors: French, SW, Bardag-Gorce, F, French, BA, Li, J, Oliva, J
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482129/
https://ncbi.nlm.nih.gov/pubmed/21820428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2011.07.004
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