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THE ROLE OF INNATE IMMUNITY IN THE PATHOGENESIS OF PRENEOPLASIA IN DRUG-INDUCED CHRONIC HEPATITIS BASED ON A MOUSE MODEL
Innate immunity factors such as conversion of the 26S proteasome to form the immunoproteasome and the Toll-like receptor signaling pathways are activated in chronic hepatitis induced by the carcinogenic drug DDC. Over time, preneoplastic hepatocyte phenotypes appear in the liver parenchyma. These ch...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3482129/ https://ncbi.nlm.nih.gov/pubmed/21820428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2011.07.004 |
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