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Strain-related differences in antibody-mediated changes in gene expression are associated with differences in capsule and location of binding

We recently established that antibody (Ab)-binding can induce gene expression changes in a serotype A strain (H99) of the pathogenic yeast, Cryptococcus neoformans. That study showed that monoclonal antibodies (mAbs) differing in epitope specificity and protective efficacy elicited differences in ge...

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Hlavní autoři: McClelland, Erin E., Casadevall, Arturo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482122/
https://ncbi.nlm.nih.gov/pubmed/22327012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fgb.2012.01.006
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