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Ab binding alters gene expression in Cryptococcus neoformans and directly modulates fungal metabolism

Abs facilitate humoral immunity via the classical mechanisms of opsonization, complement activation, Ab-dependent cellular cytotoxicity, and toxin/viral neutralization. There is also evidence that some Abs mediate direct antimicrobial effects. For example, Ab binding to the polysaccharide capsule of...

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Bibliografische gegevens
Hoofdauteurs: McClelland, Erin E., Nicola, André M., Prados-Rosales, Rafael, Casadevall, Arturo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846037/
https://ncbi.nlm.nih.gov/pubmed/20335660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38322
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