Toll-like Receptor 2 (TLR2), Transforming Growth Factor-β, Hyaluronan (HA), and Receptor for HA-mediated Motility (RHAMM) Are Required for Surfactant Protein A-stimulated Macrophage Chemotaxis

The innate immune system protects the host from bacterial and viral invasion. Surfactant protein A (SPA), a lung-specific collectin, stimulates macrophage chemotaxis. However, the mechanisms regulating this function are unknown. Hyaluronan (HA) and its receptors RHAMM (receptor for HA- mediated moti...

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Detalhes bibliográficos
Main Authors: Foley, Joseph P., Lam, David, Jiang, Hongmei, Liao, Jie, Cheong, Naeun, McDevitt, Theresa M., Zaman, Aisha, Wright, Jo Rae, Savani, Rashmin C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481337/
https://ncbi.nlm.nih.gov/pubmed/22948158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.360982
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