Structure of a Proteasome Pba1-Pba2 Complex: IMPLICATIONS FOR PROTEASOME ASSEMBLY, ACTIVATION, AND BIOLOGICAL FUNCTION

The 20S proteasome is an essential, 28-subunit protease that sequesters proteolytic sites within a central chamber, thereby repressing substrate degradation until proteasome activators open the entrance/exit gate. Two established activators, Blm10 and PAN/19S, induce gate opening by binding to the p...

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Autori principali: Stadtmueller, Beth M., Kish-Trier, Erik, Ferrell, Katherine, Petersen, Charisse N., Robinson, Howard, Myszka, David G., Eckert, Debra M., Formosa, Tim, Hill, Christopher P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Protein Structure and Folding
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481334/
https://ncbi.nlm.nih.gov/pubmed/22930756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.367003
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