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Actopaxin (α-Parvin) Phosphorylation Is Required for Matrix Degradation and Cancer Cell Invasion

Dysregulation of cell adhesion and motility is known to be an important factor in the development of tumor malignancy. Actopaxin (α-parvin) is a paxillin, integrin-linked kinase, and F-actin binding focal adhesion protein with several serine phosphorylation sites in the amino terminus that contribut...

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Detalhes bibliográficos
Main Authors: Pignatelli, Jeanine, LaLonde, Sara E., LaLonde, David P., Clarke, Dominic, Turner, Christopher E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481328/
https://ncbi.nlm.nih.gov/pubmed/22955285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.385229
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