Francisella DnaK Inhibits Tissue-nonspecific Alkaline Phosphatase

Following pulmonary infection with Francisella tularensis, we observed an unexpected but significant reduction of alkaline phosphatase, an enzyme normally up-regulated following inflammation. However, no reduction was observed in mice infected with a closely related Gram-negative pneumonic organism...

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Detalhes bibliográficos
Main Authors: Arulanandam, Bernard P., Chetty, Senthilnath Lakshmana, Yu, Jieh-Juen, Leonard, Sean, Klose, Karl, Seshu, Janakiram, Cap, Andrew, Valdes, James J., Chambers, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481318/
https://ncbi.nlm.nih.gov/pubmed/22923614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.404400
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