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Fatty Acids Change the Conformation of Uncoupling Protein 1 (UCP1)
UCP1 catalyzes proton leak across the mitochondrial inner membrane to disengage substrate oxidation from ATP production. It is well established that UCP1 is activated by fatty acids and inhibited by purine nucleotides, but precisely how this regulation occurs remains unsettled. Although fatty acids...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3481287/ https://ncbi.nlm.nih.gov/pubmed/22952235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.381780 |
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