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Synergy of fatty acid and reactive alkenal activation of proton conductance through uncoupling protein 1 in mitochondria
The kinetics of proton transport through mammalian UCP1 (uncoupling protein 1) expressed in yeast mitochondria were measured. There was little or no UCP1 activity in the absence of added palmitate, but significant activity in its presence. The activator 4-HNE (4-hydroxy-2-nonenal) had little effect...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Portland Press Ltd.
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1462701/ https://ncbi.nlm.nih.gov/pubmed/16451125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20052004 |
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