Structure and Location of the Regulatory β Subunits in the (αβγδ)(4) Phosphorylase Kinase Complex

Phosphorylase kinase (PhK) is a hexadecameric (αβγδ)(4) complex that regulates glycogenolysis in skeletal muscle. Activity of the catalytic γ subunit is regulated by allosteric activators targeting the regulatory α, β, and δ subunits. Three-dimensional EM reconstructions of PhK show it to be two lar...

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Bibliographische Detailangaben
Hauptverfasser: Nadeau, Owen W., Lane, Laura A., Xu, Dong, Sage, Jessica, Priddy, Timothy S., Artigues, Antonio, Villar, Maria T., Yang, Qing, Robinson, Carol V., Zhang, Yang, Carlson, Gerald M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481268/
https://ncbi.nlm.nih.gov/pubmed/22969083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.412874
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