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Structure and Location of the Regulatory β Subunits in the (αβγδ)(4) Phosphorylase Kinase Complex
Phosphorylase kinase (PhK) is a hexadecameric (αβγδ)(4) complex that regulates glycogenolysis in skeletal muscle. Activity of the catalytic γ subunit is regulated by allosteric activators targeting the regulatory α, β, and δ subunits. Three-dimensional EM reconstructions of PhK show it to be two lar...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3481268/ https://ncbi.nlm.nih.gov/pubmed/22969083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.412874 |
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