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A novel angiogenesis inhibitor impairs lovo cell survival via targeting against human VEGFR and its signaling pathway of phosphorylation

Colorectal cancer represents the fourth commonest malignancy, and constitutes a major cause of significant morbidity and mortality among other diseases. However, the chemical therapy is still under development. Angiogenesis plays an important role in colon cancer development. We developed HMQ18–22 (...

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Detalhes bibliográficos
Main Authors: Zhang, Y M, Dai, B L, Zheng, L, Zhan, Y Z, Zhang, J, Smith, W W, Wang, X L, Chen, Y N, He, L C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481133/
https://ncbi.nlm.nih.gov/pubmed/23059825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.145
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