Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure

Inflammation enhances the secretion of sphingomyelinases (SMases). SMases catalyze the hydrolysis of sphingomyelin into phosphocholine and ceramide. In erythrocytes, ceramide formation leads to exposure of the removal signal phosphatidylserine (PS), creating a potential link between SMase activity a...

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Bibliographische Detailangaben
Hauptverfasser: Dinkla, S, Wessels, K, Verdurmen, W P R, Tomelleri, C, Cluitmans, J C A, Fransen, J, Fuchs, B, Schiller, J, Joosten, I, Brock, R, Bosman, G J C G M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481131/
https://ncbi.nlm.nih.gov/pubmed/23076218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.143
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