Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure

Inflammation enhances the secretion of sphingomyelinases (SMases). SMases catalyze the hydrolysis of sphingomyelin into phosphocholine and ceramide. In erythrocytes, ceramide formation leads to exposure of the removal signal phosphatidylserine (PS), creating a potential link between SMase activity a...

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Autori principali: Dinkla, S, Wessels, K, Verdurmen, W P R, Tomelleri, C, Cluitmans, J C A, Fransen, J, Fuchs, B, Schiller, J, Joosten, I, Brock, R, Bosman, G J C G M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481131/
https://ncbi.nlm.nih.gov/pubmed/23076218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.143
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