Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure

Inflammation enhances the secretion of sphingomyelinases (SMases). SMases catalyze the hydrolysis of sphingomyelin into phosphocholine and ceramide. In erythrocytes, ceramide formation leads to exposure of the removal signal phosphatidylserine (PS), creating a potential link between SMase activity a...

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Main Authors: Dinkla, S, Wessels, K, Verdurmen, W P R, Tomelleri, C, Cluitmans, J C A, Fransen, J, Fuchs, B, Schiller, J, Joosten, I, Brock, R, Bosman, G J C G M
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2012
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481131/
https://ncbi.nlm.nih.gov/pubmed/23076218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.143
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