Role of novel type I interferon epsilon in viral infection and mucosal immunity

Intranasal infection with vaccinia virus co-expressing interferon epsilon (VV-HIV-IFN-ɛ) was used to evaluate the role of IFN-ɛ in mucosal immunity. VV-HIV- IFN-ɛ infection induced a rapid VV clearance in lung that correlated with (i) an elevated lung VV-specific CD8(+)CD107a(+)IFN-γ(+) population e...

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Main Authors: Xi, Yang, Day, Stephanie L, Jackson, Ronald J, Ranasinghe, Charani
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481022/
https://ncbi.nlm.nih.gov/pubmed/22617838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.35
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