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Hypermethylation of OPRM1 promoter region in European Americans with alcohol dependence
The μ-opioid receptor mediates rewarding effects of alcohol and illicit drugs. We hypothesized that altered DNA methylation in the μ-opioid receptor gene (OPRM1) might influence the vulnerability to alcohol dependence (AD). Genomic DNA was extracted from the peripheral blood of 125 European American...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3481015/ https://ncbi.nlm.nih.gov/pubmed/22914673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhg.2012.98 |
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